翻訳と辞書
Words near each other
・ Reto Delnon
・ Reto Grütter
・ Reto Götschi
・ Reto Hollenstein
・ Reto Hug
・ Reto Keller
・ Reto Lamm
・ Reto Pavoni
・ Reto Perl
・ Retinoic acid receptor beta
・ Retinoic acid receptor gamma
・ Retinoic acid syndrome
・ Retinoic acid-inducible orphan G protein-coupled receptor
・ Retinoid
・ Retinoid receptor
Retinoid X receptor
・ Retinoid X receptor alpha
・ Retinoid X receptor beta
・ Retinoid X receptor gamma
・ Retinol
・ Retinol binding protein
・ Retinol binding protein 4
・ Retinol dehydrogenase
・ Retinol isomerase
・ Retinol O-fatty-acyltransferase
・ Retinopathy
・ Retinopathy of prematurity
・ Retinoschisin
・ Retinoschisis
・ Retinoscopy


Dictionary Lists
翻訳と辞書 辞書検索 [ 開発暫定版 ]
スポンサード リンク

Retinoid X receptor : ウィキペディア英語版
Retinoid X receptor

The retinoid X receptor (RXR) is a type of nuclear receptor that is activated by 9-cis retinoic acid, which has never been convincingly proven to be of physiological relevance and to be present endogenously, as well as 9-cis-13,14-dihydro-retinoic acid. There are three retinoic X receptors (RXR): RXR-alpha, RXR-beta, and RXR-gamma, encoded by the , , genes, respectively.
RXR heterodimerizes with subfamily 1 nuclear receptors including CAR, FXR, LXR, PPAR, PXR, RAR, TR, and VDR.
As with other type II nuclear receptors, the RXR heterodimer in the absence of ligand is bound to hormone response elements complexed with corepressor protein. Binding of agonist ligands to RXR results in dissociation of corepressor and recruitment of coactivator protein, which, in turn, promotes transcription of the downstream target gene into mRNA and eventually protein.
==See also==

* Retinoic acid receptor
* Retinoid X receptor alpha
* Retinoid X receptor beta
* Retinoid X receptor gamma

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Retinoid X receptor」の詳細全文を読む



スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース

Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.